BindingDB PrimarySearch

BDBM50278314 CHEMBL1076628::sodium perosmate(VIII)

SMILES: [O-][Os]([O-])(=O)(=O)=O

InChI Key: InChIKey=OCNNBYRXULLCFR-UHFFFAOYSA-N

Data: 14 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50278314
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-carbonic anhydrase (Helicobacter pylori)	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	4.80E+5	-4.52	n/a	n/a	n/a	n/a	n/a	7.5	25
Universit� degli Studi di Firenze					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...				J Enzyme Inhib Med Chem 28: 388-91 (2013) Article DOI: 10.3109/14756366.2011.649268 BindingDB Entry DOI: 10.7270/Q2S75F7K
Universit� degli Studi di Firenze					More data for this Ligand-Target Pair
Carbonic anhydrase (Astrosclera willeyana)	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	6.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins ...				Bioorg Med Chem Lett 22: 1314-6 (2012) Article DOI: 10.1016/j.bmcl.2011.12.085 BindingDB Entry DOI: 10.7270/Q2W66M7M
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Helicobacter pylori)	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	8.90E+5	-4.16	n/a	n/a	n/a	n/a	n/a	7.5	25
Universit� degli Studi di Firenze					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...				J Enzyme Inhib Med Chem 28: 388-91 (2013) Article DOI: 10.3109/14756366.2011.649268 BindingDB Entry DOI: 10.7270/Q2S75F7K
Universit� degli Studi di Firenze					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	9.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	8.3	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3				Bioorg Med Chem Lett 21: 3591-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.105 BindingDB Entry DOI: 10.7270/Q2930TGN
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	9.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Radboud University Nijmegen Medical Centre Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	9.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assay				Bioorg Med Chem Lett 22: 1314-6 (2012) Article DOI: 10.1016/j.bmcl.2011.12.085 BindingDB Entry DOI: 10.7270/Q2W66M7M
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	9.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1-catalyzed CO2 hydration by stopped flow assay				Bioorg Med Chem Lett 19: 1855-7 (2009) Article DOI: 10.1016/j.bmcl.2009.02.088 BindingDB Entry DOI: 10.7270/Q27H1KH3
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	9.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Slovak Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assay				Bioorg Med Chem Lett 22: 1314-6 (2012) Article DOI: 10.1016/j.bmcl.2011.12.085 BindingDB Entry DOI: 10.7270/Q2W66M7M
Slovak Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	9.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Radboud University Nijmegen Medical Centre Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem 19: 243-8 (2011) Article DOI: 10.1016/j.bmc.2010.11.031 BindingDB Entry DOI: 10.7270/Q2B858D2
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	9.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2-catalyzed CO2 hydration by stopped flow assay				Bioorg Med Chem Lett 19: 1855-7 (2009) Article DOI: 10.1016/j.bmcl.2009.02.088 BindingDB Entry DOI: 10.7270/Q27H1KH3
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	9.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	8.3	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3				Bioorg Med Chem Lett 21: 3591-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.105 BindingDB Entry DOI: 10.7270/Q2930TGN
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Mus musculus (mouse))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	9.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of mouse recombinant carbonic anhydrase 13-catalyzed CO2 hydration by stopped flow assay				Bioorg Med Chem Lett 19: 1855-7 (2009) Article DOI: 10.1016/j.bmcl.2009.02.088 BindingDB Entry DOI: 10.7270/Q27H1KH3
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	1.02E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 7-catalyzed CO2 hydration by stopped flow assay				Bioorg Med Chem Lett 19: 1855-7 (2009) Article DOI: 10.1016/j.bmcl.2009.02.088 BindingDB Entry DOI: 10.7270/Q27H1KH3
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50278314 (CHEMBL1076628 \| sodium perosmate(VIII)) Show SMILES [O-][Os]([O-])(=O)(=O)=O Show InChI InChI=1S/5O.Os/q;;;;;-2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC sid UniChem	Article PubMed	1.06E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 4-catalyzed CO2 hydration by stopped flow assay				Bioorg Med Chem Lett 19: 1855-7 (2009) Article DOI: 10.1016/j.bmcl.2009.02.088 BindingDB Entry DOI: 10.7270/Q27H1KH3
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair